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Our Company

Story & Identity

MDoloris Medical Systems is a French medtech created in 2010 through a public-private partnership based on the work of Pr. Régis LOGIER, Dr. MATHIEU JEANNE, Julien DE JONCKHEERE & Dr. Michel DELECROIX  (INSERM Unit 807 – CIC-IT at University Hospital).


The founding R&D link has been particularly strong throughout these years of privileged collaboration continues with this world-renowned team.

MDoloris’ innovation, its scientific and medical breakthrough, has been to research, evaluate and validate a new biological measure, a new physiological datum for measuring pain or perceived suffering.

And it is the instantaneous measurement of the autonomic nervous system’s response to painful stimuli, through the continuous measurement of cardiac variability, that has provided us today with a simple indicator, a number from 1 to 100, representing the parasympathetic tone of the human body.

This new reference beacon is obviously of great importance in certain specific circumstances, particularly in surgery.


This technology has given a rise to MDoloris products, mainly used in neonatal monitoring and in adult and pediatric anesthesiology.


MDoloris’ proprietary and patented technology has been the subject of more than 230 independent international scientific publications. Today, more than half a million hospital patients have already benefited from this technology.

After successfully developing the MDoloris technology and an assessment index (ANI-NIPE) for unconscious patients, MDoloris turned its attention to adapting its MDoloris technology to other living conditions and transposed the technology and the assessment of the autonomic nervous system to the conscious patient, again with a view to assessing comfort and well-being.
This new phase of R&D has recently opened up new prospects in hospitals (monitoring in intensive care with the development of an additional index - vital energy) and outside (portable device for nursing homes, palliative care, etc).

The Vision

Today, the patented and proprietary MDoloris Technology is based on solid scientific and clinical foundations and takes anesthesiology and the assessment of patient comfort / suffering to a new level, offering greater safety and objective continuous monitoring.
MDoloris Technology is changing day-to-day practice in a wide range of medical fields and procedures and offers many opportunities for today and for the future as it enables pain and comfort to be assessed objectively, whether the patient is conscious or unconscious.

Our Team

MDoloris Management

“Our company’s motto, measure the autonomic nervous system, take control and improve outcomes; has been driving each member of the MDoloris Medical Systems team since the company’s inception in June 2010.

Since day one, MDoloris has overcome many obs­tacles thanks to our exceptionally dedicated team members. Yet we have still delivered even during the Covid crisis. This team dedication is the foun­dation of our success.”

Fabien PAGNIEZCEO Founder

Fabien Pagniez

CEO, Founder

Ignacio Gonzalez

Chief Medical Officer

Julien Legrand

Chief Financial Officer

Jean-Marc Mosselmans

Strategic & Marketing Director